Teaching

I have been a demonstrator in neuro-anatomy and a lecturer at Brighton & Sussex Medical School. I have lectured on sleep disorders nationally. I currently lecture to Medical Students on the Neueoscience & behaviour module at Brighton & Sussex Medical School. I also give regular lectures to GP’s and teach Neurology to training grade Neurologists.

Research

I have published laboratory-based research in Parkinson’s Disease at The Institute of Neurology, The Parkinson’s Disease Society Brain Bank & in London. This involved the use of in situ hybridization of neurotransmitter mRNAs in various brain basal ganglia regions in post-mortem Parkinson’s disease brains. I am currently undertaking studies in patients with the non-REM parasomnia spectrum (sleep walking, night terrors, confusional arousals etc).

Selected Papers (To request a copy please use the contact form by clicking here)

• Sleep walking
• BMJ Lesson of the Week – Diaphragm Paralysis
• Discovery of Nitric Oxide Neurons in the Subthalamic Nucleu
• Basal ganglia enkephalin & substance-P mRNA expression in human Parkinson’s disease
• Basal ganglia GAD-67 mRNA expression in human Parkinson’s disease
• Diagnosis of nerve damage in cancer

All My Publications

A.P. NISBET and C.A. MARSDEN (1984)

Increased behavioural response to 5-methoxy-n,n-dimethyl-tryptamine, but not to RU 24969, after intra-ventricular 5,7-dihydroxy-tryptamine administration. European Journal of pharmacology, 104, 177-180.

M.P. BRAZELL, C.A. MARSDEN, A.P. NISBET and C. ROUTLEDGE (1985)

The 5-HT receptor agonist RU-24969 decreases 5-hydroxytryptamine (5-HT) release and metabolism in the rat frontal cortex in vitro and in vivo. British Journal of Pharmacology, 86, 209-216.

A.P. NISBET, W. KINEAR and M.J. WARD (1991)

Bilateral diaphragmatic paralysis may present with orthopnoea and apparent radiological evidence of pulmonary emboli. British Medical Journal, 302, 954-955.

A.P.NISBET, O.J.F. FOSTER, A. KINGSBURY, A.J.LEES, C.D. MARSDEN (1994)

Nitric oxide synthase mRNA expression in human subthalamic nucleus, striatum and globus pallidus: implications for basal ganglia function. Brain Res. Mol. Brain Res., 22: 329-332

A.P.NISBET, O.J.F. FOSTER, A. KINGSBURY, A.J.LEES (1994)

Regional striatal neuropeptide expression in Parkinson’s disease: a quantitative in situ hybridisation study (Abstract). New Trends in Clinical Neuropharmacology, 7 (N.1): 60.

A.P.NISBET, O.J.F. FOSTER, A. KINGSBURY, C.D. MARSDEN, A.J.LEES (1994)

Nitric oxide synthase mRNA expression in parkinsonian basal ganglia: A Quantitative In Situ Hybridization Study (Abstract). Mov.Disord. 9 (Suppl.1): 103

A. KINGSBURY, O.J.F. FOSTER, A.P. NISBET, N. CAIRNS, L. BRAY, D.J. EVE, A.J.LEES, C.D. MARSDEN (1995)

Tissue pH as an indicator of mRNA preservation in human post-mortem brain. Mol.Brain Res. 28: 311-318

A.P. NISBET, O.J.F. FOSTER, A. KINGSBURY, D.J. EVE, S.E. DANIEL,C.D. MARSDEN, A.J.LEES (1995)

Pre-proenkephalin and pre-protachykinin mRNA expression in normal human basal ganglia and in Parkinson’s disease. Neuroscience 66: 361-376

D.J. EVE, A.P.NISBET, A.KINGSBURY, C.D. MARSDEN, O.J.FOSTER (1995)

Somatostatin mRNA expression in parkinsonian basal ganglia. A quantitative in situ hybridization study (Abstract). Soc.Neurosci.Abs. 21: 1251

A.P. NISBET, D.J. EVE, A. KINGSBURY, S.E. DANIEL, C.D. MARSDEN, A.J.LEES, O.J.F. FOSTER (1996)

Glutamate decarboxylase-67 messenger RNA expression in normal human basal ganglia and in Parkinson’s disease. Neuroscience 75: 389-406

A.P. NISBET, C. DAVENPORT, I. TODD, J.M. DAVIES,A.M. WHITELEY (1996)

Paraneoplastic ‘stiff-man syndrome plus’ associated with an IgM kappa-secreting non-Hodgkin’s lymphoma (Abstract). Mov.Disord. 11 (Suppl 1.): 235

B.S. ATHWAL, A.P. NISBET, D. JEFFERSON (1996)

Diaphragmatic flutter associated with an intramedullary cervical cord tumour (Abstract). Mov.Disord. 11 (Suppl 1.): 98

A.P. NISBET, N.J. SMITH, R.B. GODWIN-AUSTEN (1996)

Aquired epileptic expressive dysphasia in a sinistral patient associated with increased ictal 99mTc-HMPAO uptake in the right fronto-temporal region (Abstract). Eur.J.Neurology 3 (suppl 5): 143

A.P. NISBET, S.E. DANIEL, A.J. LEES (1996)

Arteriosclerotic Parkinsonism (Abstract). J.Neurol.Neurosurg.Psychiatry 61: 537

D.J. EVE, A.P. NISBET, A. KINGSBURY, C.D. MARSDEN, O.J.F. FOSTER (1997)

Increased nitric oxide expression within the the subthalamic nucleus in Parkinson’s disease (Abstract). Mov.Disord. 12 (Suppl 1.): 115

VE DJ, NISBET AP, KINGSBURY AE, TEMLETT J, MARSDEN CD, FOSTER OJ. (1997)

Selective increase in somatostatin mRNA expression in human basal ganglia in Parkinson’s disease. Brain Res Mol Brain Res. 1997: 50(1-2): 59-70.

EVE DJ. NISBET AP. KINGSBURY AE. HEWSON EL. DANIEL SE. LEES AJ. MARSDEN CD. FOSTER OJ. (1998)

Basal ganglia neuronal nitric oxide synthase mRNA expression in Parkinson’s disease. Brain Research. Molecular Brain Research. 63(1):62-71, 1998

ONG GL, RIPLEY LG, NISBET AP (2000)

Temporal Modulation (8Hz Flicker) Enhances the Difference in Achromatic Contrast Sensitivity Between Parkinson’s Disease Patients and Controls Especially at Low Spatial Frequency. Movement Disorder; 15 (Suppl 3):82

ONG GL, NISBET AP, HADDRELL NR, BRADLEY VA, RIPLEY LG (1999)

Levodopa Responsiveness of Contrast Sensitivity in Different Parkinsonian Syndromes. Parkinsonism & Related Disorders; 5 (Suppl):S39

FORBES A, BRECHANY U, STEGIE F, STUTT A, CHAUDHURI KR, APPIAH-KUBI LS, NISBET A, BURN DJ

Use and Tolerability of Cabergoline in Young and Older People with Parkinson’s Disease: A Multi-Center Observational Study. The Journal of Applied Research Vol. 3 (4), 2003

DAS R, MOLLOY J, NISBET A

Acute onset new variant creutzfeld-jakob disease in a compulsive jelly eater. J. Neurol. Neurosurg. Psychiatry 2002;73;223

22. ANDERSON S, NISBET A, DAS R, MALLOY J

A case study in variant CJD. Archives of Clinical Neuropsychology 19 (2004) 847

HARRISON NA, CHURCH A, NISBET A, RUDGE P, GIOVANNONI G.

Late recurrences of Sydenham’s chorea are not associated with anti-basal ganglia antibodies. J Neurol Neurosurg Psychiatry. 2004 Oct;75(10):1478-9

24. HARPER A, BAYLISS M, SAHA R, SCUTT A, NISBET A

Late onset dopa-responsive dystonia with tremor, gait freezing and behavioural disturbance and a normal dopamine transporter scan. Age Ageing. 2008 Nov;37(6):719-20

E. BROUGHTON, A. GRICKS, S. BAYNES, A. NISBET

Comparing a bedside timed motor assessment tool (BT-MAT) with the UPDRS- III to measure clinical features and l-dopa response in parkinson’s disease

KAREN M DOHERTY, ALASTAIR J NOYCE, LAURA SILVEIRA-MORIYAMA, ANGUS NISBET, NIALL QUINN, ANDREW J LEES

Familial camptocormia: from dystonia to myopathy J Neurol Neurosurg Psychiatry. 2012 Mar;83(3):350-1

BANERJEE D, NISBET A.

Sleepwalking. Sleep Med Clin. 2011 6 (4): 401–416.

LAURA MANTOAN SOFIA H ERIKSSON ANGUS P NISBET MATTHEW C WALKER

Adult-onset Non-REM Parasomnia with Hypnopompic Hallucinatory Pain: a Case Report Sleep. 2013 Feb 1;36(2):287-90.

29. BREJT N, BERRY J, NISBET A, BLOOMFIELD D, BURKILL G.

Pelvic radiculopathies, lumbosacral plexopathies, and neuropathies in oncologic disease: a multidisciplinary approach to a diagnostic challenge. Cancer Imaging. 2013 Dec 30;13(4):591-601.

30. LANE R, NISBET, A

Stroke mimic diagnoses presenting to a hyper-acute stroke unit Clinical Medicine (Lond). 2017 Apr;17(2):190-191.

31. CHRIS BIRD, ANGUS NISBET, CHRISTIANE OEDEKOVEN, JAMES L. KEIDEL, STUART ANDERSON

Effects of amnesia on processing in the hippocampus and default mode network during a naturalistic memory task: a case study Neuropsychologia. 2019 Sep;132:107104. doi: 10.1016/j.neuropsychologia.2019.05.022. Epub 2019 Jun 29.(Corresponding author with Chris Bird)

32. EVA MJ DE BOER, ANDREW W BARRITT, MARWA ELAMIN, STUART J ANDERSON, REBECCA BROAD, ANGUS NISBET, H STEPHAN GOEDEE, JOOST VAN IERSEL, MALU PARSON, JUAN F VAZQUEZ COSTA, JOHANNES PRUDLO, CHRISTIAN A VEDELER, JULIO PARDO FERNANDEZ, MÓNICA POVEDANO PANADES, MARIA A ALBERTI AGUILO, ELEONORA DALLA BELLA, OLIVER HARSCHNITZ, LEONHARD H VAN DEN BERG, JAN H VELDINK, AMMAR AL-CHALABI, PETER N LEIGH AND MICHAEL A VAN ES.

An update on facial onset sensory and motor neuronopathy; new cases, cognitive involvement, diagnostic criteria and pathophysiology In Press Neurology Clinical Practice 2020